9ème congrès de la Société Francophone de Thérapie Cellulaire et Génique Paris, 13-15 Juin 2010
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| SUNDAY JUNE 13 | |
| 13h45 | Opening ceremony |
| 14h00- 14h45 | Special lecture : Thierry HEIDMANN (UMR-8122, IGR, France) Endogenous retroviruses and the placental "syncytins": natural history of reiterated and successful retroviral gene transfers in the course of mammal evolution |
| 14h45- 16h45 | Gene therapy for the central nervous system Nicole DEGLON (CEA, Fontenay aux roses, France) Pre-clinical studies of neurodegenerative diseases Stéphane PALFI (Hôpital H. Mondor / Créteil, I2BM CEA/ Inserm, France) Gene therapy in Parkinson disease: from pre-clinical studies in primates to phase I/II clinical trials. 4 Selected oral presentations |
| 16h45- 17h15 |
Coffee break |
| 17h15- 19h15 | David FINK (Dpt of Neurology, University of Michigan, USA)
A phase I clinical trial of gene transfer for the treatment of intractable pain Patrick AUBOURG (UMR-745, Hôpital St Vincent de Paul, Paris) |
| 19h15-21h00 |
Poster session (viewing) & welcome reception |
| MONDAY JUNE 14 | |
| 8h30-10h45 |
Non-viral Gene Therapy Session Erina A LEVASHINA (UMR-963, IBMC, Strasbourg) Functional dissection of mosquito immune responses by RNAi - opportunities and limitations Gilles DIVITA (UMR-5237, Centre de Recherches de Biochimie Macromoléculaire, Montpellier) Peptide-based nanoparticles for in vivo delivery of siRNA Virginie ESCRIOU (UMR-8151, Inserm U1022, Fac pharma, Paris) Efficient lipoplexes for administration of siRNA 3 Selected oral presentations |
| 10h45-11h15 | Coffee Break |
| 11h15-13h00 |
Vaccinology – Immunotherapy – Infectious diseases Laurent FISCHER Merial, LyonPowerful cellular immunity to two sand fly salivary proteins in dogs: could this set the stage for a superior anti-Leishmania vaccine? Wei- Zen WEI (Wayne State University, Detroit, MI, USA) DNA vaccines in cancer therapy 3 Selected oral presentations |
| 13h00- 15h00 | LUNCH |
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POSTER SESSION I |
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| 15h00-16h00 |
General Assembly of SFTCG |
| 16h00-18h30 | Cell Therapy Session CD4+CD25+ regulatory T-cell depletion improves the graft-versus-tumor effect of donor lymphocytes after allogeneic hematopoietic stem cell transplantation François PATTOU (U857, CHR de Lille) Cell therapy for diabetEs: Where ? Human embryonic stem-cell derivatives for full reconstruction of the pluristratified epidermis: a preclinical study
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| TUESDAY JUNE 15 | |
| Special thematic session: “Targeted integration, epigenetic and chromatin regulation” | |
| 8h30-10h15 | Homologous Recombination Meganucleases and gene therapy: different strategies |
| 10h15-10h45 | Coffee Break |
| 10h45-11h45 |
Homologous Recombination: applications Combining Site-Specific Integration and Cassette Design to Achieve Robust Expression without Impacting Endogenous Gene Expression Ignacio ANEGON (UMR-643, Nantes, France) Zinc-finger nucleases: a powerful tool for genetic engineering of animals |
| 11h45-13h00 | POSTER SESSION II |
| 13h00-14h00 | LUNCH |
| 14h00-15h30 |
Epigenetics, chromatin and nuclear organization Gene regulation: from chromatin structure to nuclear compartmentalization Chromatin marks and subnuclear positioning at lineage-affiliated genetic programs to predict differentiation potential of multipotent hematopoietic progenitors Manuel GREZ (Institute for Biomedical Research, Frankfurt, Germany) A lentiviral vector for the correction of Chronic Granulomatous Disease containing a chromatin opening element provides copy-dependent expression and resistance to CpG methylation. |
| 15h30-16h00 | Best oral presentation and best poster awards |
| Closure | |