Daniela Cesana

Daniela Cesana is currently Project Leader at San Raffaele Telethon Institute for Gene Therapy in the Safety and Insertional Mutagenesis unit. She started her career in 2003 establishing a preclinical mouse model that revealed and dissected the mechanisms of genotoxicity of integrating vectors. She also found that, like other retroviruses, HIV-1 takes advantage of insertional mutagenesis to favor its persistence in the host. More recently, she developed technologies allowing the retrieval of integration sites from cell-free DNA and providing insights into AAV biology.