Serena Scala

Serena Scala is Project Leader in the group of Alessandro Aiuti at San Raffaele Telethon Institute for Gene Therapy (SR-Tiget) in Milan. She is PhD in Molecular Medicine. Her main interests are human hematopoietic stem/progenitor cells, gene therapy and integration site-clonal tracking. Her works combine deep multi-parametric phenotyping, integration site analyses and single-cell transcriptomic with state-of-the-art functional assays for studying the biology of the hematopoietic stem progenitor cells and their dynamics during hematopoietic reconstitution upon gene therapy. She is currently investigating the role of distinct sources of hematopoietic stem/progenitor subpopulations on the study of HSPC trafficking, mobilization and long-term clonality in GT patients. She developed with her collaborators a novel flow-cytometry technology with numerous clinical and pre-clinical applications in the field of hematology, recently patented.