Mario Squadrito

Mario Leonardo Squadrito graduated in 2008 at the University of L’Aquila. In 2012, he obtained a PhD degree in Molecular and Cellular Biology from the San Raffaele University (Milan, IT) and the Open University (UK); in the course of his PhD studies, he identified and characterized of a new microRNA, miR-511-3p, highly expressed in tumor-associated macrophages. In 2012, he joined the EPFL (Lausanne, CH) where he identified a mechanism whereby miRNAs are sorted to microvesicles and trasfer to acceptor cells. He also designed new strategies to genetically reprogram TAMs to activate immune functions. He also invented a platform to exploit circulating microvesicles as a source of tumor antigens for innovative tumor vaccines. Since 2024, he has been appointed Group Leader at the San Raffaele Telethon Institute for Gene Therapy, Milan, Italy.